ATF7 anticorps (AA 1-117)
Aperçu rapide pour ATF7 anticorps (AA 1-117) (ABIN7148809)
Antigène
Voir toutes ATF7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1-117
-
Fonction
- ATF7 Antibody
-
Purification
- Antigen Affinity Purified
-
Immunogène
- Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 protein (1-117AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- ATF7 (Activating Transcription Factor 7 (ATF7))
-
Autre désignation
- ATF7
-
Sujet
-
Background: Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5\\\'-GTGACGT[AG][AG]-3\\\'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Aliases: 1110012F10Rik antibody, 9430065F09Rik antibody, Activating transcription factor 7 antibody, AI549878 antibody, ATF7 antibody, Atf7 protein antibody, ATF7_HUMAN antibody, ATFA antibody, C130020M04Rik antibody, cAMP-dependent transcription factor ATF-7 antibody, Cyclic AMP-dependent transcription factor ATF 7 antibody, Cyclic AMP-dependent transcription factor ATF-7 antibody, MGC31554 antibody, MGC57182 antibody, Transcription factor ATF A antibody, Transcription factor ATF-A antibody
-
UniProt
- P17544
Antigène
-