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CPEB4 anticorps (AA 244-515) (Biotin)

CPEB4 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7149349
  • Antigène Tous les produits CPEB4
    CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
    Épitope
    • 8
    • 8
    • 6
    • 4
    • 1
    • 1
    AA 244-515
    Reactivité
    • 29
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CPEB4 est conjugé à/à la Biotin
    Application
    • 20
    • 17
    • 13
    • 3
    • 2
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Cytoplasmic polyadenylation element-binding protein 4 protein (244-515AA)
    Isotype
    IgG
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
    Autre désignation
    CPEB4 (CPEB4 Produits)
    Synonymes
    anticorps DKFZp468L052, anticorps 4930447D24Rik, anticorps AI851572, anticorps mKIAA1673, anticorps Cpeb3, anticorps zgc:66166, anticorps cytoplasmic polyadenylation element binding protein 4, anticorps cytoplasmic polyadenylation element binding protein 4 S homeolog, anticorps cytoplasmic polyadenylation element binding protein 4a, anticorps CPEB4, anticorps cpeb4, anticorps cpeb4.S, anticorps Cpeb4, anticorps cpeb4a
    Sujet

    Background: Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\\\'-UUUUUAU-3\\\') within the mRNA 3\\\'-UTR (PubMed:24990967). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (PubMed:27857118). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (By similarity).

    Aliases: CPE binding protein 4 antibody, CPE-binding protein 4 antibody, CPE-BP4 antibody, cpeb4 antibody, CPEB4_HUMAN antibody, Cytoplasmic polyadenylation element binding protein 4 antibody, Cytoplasmic polyadenylation element-binding protein 4 antibody, hCPEB-4 antibody, KIAA1673 antibody

    UniProt
    Q17RY0
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