CKAP5 anticorps (AA 1802-2019)

N° du produit ABIN7149368

Cet anticorps Lapin Polyclonal détecte spécifiquement CKAP5 dans WB, ELISA, IF et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour CKAP5 anticorps (AA 1802-2019) (ABIN7149368)

Antigène: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKAP5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-CKAP5 anticorps

Épitope: AA 1802-2019

Fonction: CKAP5 Antibody

Réactivité croisée: Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Cytoskeleton-associated protein 5 protein (1802-2019AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CKAP5

Antigène: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Autre désignation: CKAP5

Sujet:

Background: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448).

Aliases: CKAP5 antibody, KIAA0097Cytoskeleton-associated protein 5 antibody, Colonic and hepatic tumor overexpressed gene protein antibody, Ch-TOG antibody

UniProt: Q14008

Pathways: M Phase