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DACH1 anticorps (AA 166-369) (HRP)

DACH1 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7149479
  • Antigène Voir toutes DACH1 Anticorps
    DACH1 (Dachshund 1 (DACH1))
    Épitope
    • 15
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 166-369
    Reactivité
    • 50
    • 17
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 50
    • 1
    Lapin
    Clonalité
    • 51
    Polyclonal
    Conjugué
    • 24
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DACH1 est conjugé à/à la HRP
    Application
    • 44
    • 22
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Dachshund homolog 1 protein (166-369AA)
    Isotype
    IgG
    Top Product
    Discover our top product DACH1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    DACH1 (Dachshund 1 (DACH1))
    Autre désignation
    DACH1 (DACH1 Produits)
    Synonymes
    anticorps DACH, anticorps AI182278, anticorps Dac, anticorps Dach, anticorps E130112M23Rik, anticorps dach, anticorps dachshund family transcription factor 1, anticorps dachshund 1 (Drosophila), anticorps dachshund family transcription factor 1 S homeolog, anticorps dachshund homolog 1, anticorps DACH1, anticorps Dach1, anticorps dach1.S, anticorps dach1, anticorps LOC100550020
    Sujet

    Background: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).

    Aliases: DACH antibody, Dach1 antibody, DACH1_HUMAN antibody, Dachshund family transcription factor 1 antibody, dachshund homolog 1 (Drosophila) antibody, Dachshund homolog 1 antibody, Dachsund homolog 1 antibody, FLJ10138 antibody, OTTHUMP00000018494 antibody

    UniProt
    Q9UI36
    Pathways
    Feeding Behaviour
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