DOCK1 anticorps (AA 1676-1865) (FITC)

N° du produit ABIN7149581

Cet anticorps Lapin Polyclonal détecte spécifiquement DOCK1 dans . Il présente une réactivité envers Humain.

Aperçu rapide pour DOCK1 anticorps (AA 1676-1865) (FITC) (ABIN7149581)

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK1 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-DOCK1 anticorps (FITC)

Épitope: AA 1676-1865

Fonction: DOCK1 Antibody, FITC conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DOCK1

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Autre désignation: DOCK1

Sujet:

Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).

Aliases: 180 kDa protein downstream of CRK antibody, Ced5 antibody, Dedicator of Cytokinesis 1 antibody, Dedicator of cytokinesis protein 1 antibody, DOCK 1 antibody, DOCK 180 antibody, DOCK1 antibody, DOCK1_HUMAN antibody, DOCK180 antibody

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor