DHRS2 anticorps (AA 1-300)

N° du produit ABIN7149618

L’anticorps Lapin Polyclonal anti-DHRS2 a été validé pour ELISA et IHC. Il convient pour détecter DHRS2 dans des échantillons de Humain.

Aperçu rapide pour DHRS2 anticorps (AA 1-300) (ABIN7149618)

Antigène: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHRS2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DHRS2 anticorps

Épitope: AA 1-300

Fonction: DHRS2 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DHRS2

Antigène: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Autre désignation: DHRS2

Sujet:

Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

Aliases: DHRS2 antibody, SDR25C1 antibody, Dehydrogenase/reductase SDR family member 2 antibody, mitochondrial antibody, EC 1.1.1.- antibody, Dicarbonyl reductase HEP27 antibody, Protein D antibody, Short chain dehydrogenase/reductase family 25C member 1 antibody

UniProt: Q13268

Pathways: C21-Steroid Hormone Metabolic Process