RAD51D anticorps (AA 1-328)

N° du produit ABIN7150291

Détail du produit anti-RAD51D anticorps

Antigène: RAD51D (RAD51 Homolog D (RAD51D))

Épitope: AA 1-328

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human DNA repair protein RAD51 homolog 4 protein (1-328AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAD51D

Antigène: RAD51D (RAD51 Homolog D (RAD51D))

Autre désignation: RAD51D (RAD51D Produits)

Synonymes: anticorps R51H3, anticorps Rad51l3, anticorps TRAD, anticorps RAD51 paralog D, anticorps Rad51d

Sujet:

Background: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

Aliases: BROVCA4 antibody, DNA repair protein RAD51 homolog 4 antibody, HsTRAD antibody, OTTHUMP00000163851 antibody, OTTHUMP00000163852 antibody, OTTHUMP00000163853 antibody, R51H3 antibody, RA51D_HUMAN antibody, RAD51 homolog D (S. cerevisiae) antibody, RAD51 homolog D antibody, RAD51 like 3 (S. cerevisiae) antibody, RAD51 paralog D antibody, RAD51, S. cerevisiae, homolog of, D antibody, RAD51-like protein 3 antibody, Rad51l3 antibody, Recombination repair protein antibody, S. cerevisiae RAD51-like 3 antibody, TRAD antibody

UniProt: O75771