NDEL1 anticorps (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1) (pThr219) (HRP)

Details for Product anti-NDEL1 Antibody No. ABIN710840
Antigène
  • EOPA
  • MITAP1
  • NDE1L1
  • NDE2
  • NUDEL
  • NUDE2
  • Nudel
  • 2600006O07Rik
  • mNudel
  • wu:fi23c04
  • wu:fi23e06
  • eopa
  • mitap1
  • ndel1
  • ndel1-a
  • ndel1-b
  • nudel
  • nudE neurodevelopment protein 1 like 1
  • nudE neurodevelopment protein 1-like 1
  • nudE neurodevelopment protein 1-like 1b
  • nudE neurodevelopment protein 1 like 1 L homeolog
  • NDEL1
  • Ndel1
  • ndel1b
  • ndel1.L
Épitope
pThr219
23
15
15
7
4
2
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
140
105
101
4
2
Hôte
Lapin
118
21
1
Clonalité
Polyclonal
Conjugué
Cet anticorp NDEL1 est conjugé à/à la HRP
7
7
7
7
7
7
7
4
4
4
4
4
4
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
72
52
21
20
20
18
18
3
2
1
1
1
1
Options
Immunogène KLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Thr219
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others NDEL1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Ndel1 (NDEL1 Antibody Extrait)
Sujet

Nudel is important for normal cortical development. It is invovled in microtubule organization, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50 % identity with mouse and human NUDE proteins.

Synonyms: NDEL1phospho T219, Nudelphospho T219, A. nidulans, DKFZp451M0318, ENDOOLIGOPEPTIDASE A, EOPA, MITAP 1, MITAP1, Mitosin associated protein 1, Mitosin associated protein MITAP1, Mitosin-associated protein 1, Ndel 1, Ndel1, NDEL1_HUMAN, Nuclear distribution gene E like homolog 1, Nuclear distribution protein nudE like 1, Nuclear distribution protein nudE-like 1, NUDE like protein, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDEL, Protein Nudel.

ID gène 81565
Pathways Regulation of Cell Size
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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