CBX4 anticorps (AA 401-560)

N° du produit ABIN7150954

Cet anticorps anti-CBX4 est un anticorps Lapin Polyclonal détectant CBX4 dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour CBX4 anticorps (AA 401-560) (ABIN7150954)

Antigène: CBX4 (Chromobox Homolog 4 (CBX4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CBX4 anticorps

Épitope: AA 401-560

Fonction: CBX4 Antibody

Purification: Antigen Affinity purified

Immunogène: Recombinant Human E3 SUMO-protein ligase CBX4 protein (401-560AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CBX4

Antigène: CBX4 (Chromobox Homolog 4 (CBX4))

Autre désignation: CBX4

Sujet:

Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility.

Aliases: CBX 4 antibody, CBX4 antibody, Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody, CBX4_HUMAN antibody, Chromobox homolog 4 (Pc class homolog, Drosophila) antibody, Chromobox homolog 4 antibody, Chromobox protein homolog 4 antibody, E3 SUMO protein ligase CBX 4 antibody, E3 SUMO protein ligase CBX4 antibody, E3 SUMO-protein ligase CBX4 antibody, hPc 2 antibody, hPc2 antibody, NBP 16 antibody, NBP16 antibody, NS5ATP1 binding protein 16 antibody, Pc 2 antibody, Pc class 2 homolog antibody, Pc class homolog antibody, Pc class homolog Drosophila antibody, PC2 antibody, Polycomb 2 homolog antibody

UniProt: O00257