RNF40 anticorps (AA 471-724)

N° du produit ABIN7150991

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF40 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RNF40 anticorps (AA 471-724) (ABIN7150991)

Antigène: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF40 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RNF40 anticorps

Épitope: AA 471-724

Fonction: RNF40 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human E3 ubiquitin-protein ligase BRE1B protein (471-724AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RNF40

Antigène: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Autre désignation: RNF40

Sujet:

Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of \'Lys-120\' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 \'Lys-4\' and \'Lys-79\' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

Aliases: 95 kDa retinoblastoma associated protein antibody, 95 kDa retinoblastoma protein binding protein antibody, 95 kDa retinoblastoma-associated protein antibody, BRE 1B antibody, BRE1 B antibody, BRE1 E3 ubiquitin ligase homolog B antibody, BRE1-B antibody, BRE1B antibody, BRE1B_HUMAN antibody, DKFZp686K191 antibody, E3 ubiquitin protein ligase BRE1B antibody, E3 ubiquitin-protein ligase BRE1B antibody, KIAA0661 antibody, MGC13051 antibody, Rb associated protein antibody, RBP 95 antibody, RBP95 antibody, RING finger protein 40 antibody, Ring finger protein 40 E3 ubiquitin protein ligase antibody, RNF 40 antibody, Rnf40 antibody, STARING antibody

UniProt: O75150