MKRN1 anticorps (AA 109-209) (FITC)
Aperçu rapide pour MKRN1 anticorps (AA 109-209) (FITC) (ABIN7151061)
Antigène
Voir toutes MKRN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 109-209
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Fonction
- MKRN1 Antibody, FITC conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human E3 ubiquitin-protein ligase makorin-1 protein (109-209AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
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Autre désignation
- MKRN1
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Sujet
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Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription.
Aliases: E3 ubiquitin-protein ligase makorin-1 antibody, FLJ21334 antibody, HGNC:7112 antibody, Makorin antibody, Makorin ring finger protein 1 antibody, MKRN 1 antibody, mkrn1 antibody, MKRN1_HUMAN antibody, OTTHUMP00000212117 antibody, OTTHUMP00000212118 antibody, OTTHUMP00000212121 antibody, OTTHUMP00000212124 antibody, Ring finger protein 1 antibody, RING finger protein 61 antibody, RNF61 antibody
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UniProt
- Q9UHC7
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Pathways
- Chromatin Binding
Antigène
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