TRIM13 anticorps (AA 40-310)

N° du produit ABIN7151242

Cet anticorps anti-TRIM13 est un anticorps Lapin Polyclonal détectant TRIM13 dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour TRIM13 anticorps (AA 40-310) (ABIN7151242)

Antigène: TRIM13 (Tripartite Motif Containing 13 (TRIM13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM13 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TRIM13 anticorps

Épitope: AA 40-310

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRIM13

Antigène: TRIM13 (Tripartite Motif Containing 13 (TRIM13))

Autre désignation: TRIM13

Sujet:

Background: E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.

Aliases: B cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, B-cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, CAR antibody, DLEU5 antibody, E3 ubiquitin-protein ligase TRIM13 antibody, HGNC:9976 antibody, LEU5 antibody, Leukemia associated protein 5 antibody, Leukemia-associated protein 5 antibody, Putative tumor suppressor RFP2 antibody, Ret finger protein 2 antibody, RFP2 antibody, RING finger protein 77 antibody, RNF77 antibody, TRI13_HUMAN antibody, Trim13 antibody, Tripartite motif protein 13 antibody, Tripartite motif-containing protein 13 antibody

UniProt: O60858