TRIM33 anticorps (AA 1-273)

N° du produit ABIN7151258

Détail du produit anti-TRIM33 anticorps

Antigène: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Épitope: AA 1-273

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM33 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase TRIM33 protein (1-273AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRIM33

Antigène: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Autre désignation: TRIM33 (TRIM33 Produits)

Synonymes: anticorps TRIM33, anticorps ptc7, anticorps rfg7, anticorps tf1g, anticorps tif1g, anticorps tifgamma, anticorps MGC146665, anticorps tif1gamma, anticorps ECTO, anticorps PTC7, anticorps RFG7, anticorps TF1G, anticorps TIF1G, anticorps TIF1GAMMA, anticorps TIFGAMMA, anticorps ecto, anticorps 8030451N04Rik, anticorps AI413936, anticorps Ecto, anticorps Tif1g, anticorps ectodermin, anticorps mKIAA1113, anticorps cb1085, anticorps id:ibd2175, anticorps mon, anticorps wu:fc17f10, anticorps zgc:136680, anticorps tripartite motif containing 33, anticorps tripartite motif containing 33 L homeolog, anticorps tripartite motif-containing 33, anticorps TRIM33, anticorps trim33, anticorps trim33.L, anticorps Trim33

Sujet:

Background: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).

Aliases: 8030451N04Rik antibody, AI413936 antibody, cb1085 antibody, DKFZp586K1123 antibody, E3 ubiquitin-protein ligase TRIM33 antibody, EC 6.3.2.- antibody, Ectodermin antibody, Ectodermin homolog antibody, FLJ11429 antibody, FLJ32925 antibody, id:ibd2175 antibody, MGC136680 antibody, mKIAA1113 antibody, OTTHUMP00000013662 antibody, OTTHUMP00000013663 antibody, Protein Rfg7 antibody, PTC7 antibody, Ret fused gene 7 antibody, RET-fused gene 7 protein antibody, RFG7 antibody, Rfg7 protein antibody, TF1G antibody, TIF1 gamma antibody, TIF1-gamma antibody, TIF1G antibody, TIF1GAMMA antibody, TIFGAMMA antibody, Transcription intermediary factor 1-gamma antibody, Transcriptional intermediary factor 1 gamma antibody, TRI33_HUMAN antibody, trim33 antibody, Tripartite motif containing 33 antibody, Tripartite motif containing 33 protein antibody, tripartite motif-containing 33 antibody, Tripartite motif-containing protein 33 antibody, wu:fc17f10 antibody, zgc:136680 antibody

UniProt: Q9UPN9