UBR2 anticorps (AA 101-439)

N° du produit ABIN7151297

Cet anticorps Lapin Polyclonal détecte spécifiquement UBR2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour UBR2 anticorps (AA 101-439) (ABIN7151297)

Antigène: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UBR2 anticorps

Épitope: AA 101-439

Fonction: UBR2 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBR2

Antigène: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Autre désignation: UBR2

Sujet:

Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Aliases: UBR2 antibody, C6orf133 antibody, KIAA0349 antibody, E3 ubiquitin-protein ligase UBR2 antibody, EC 2.3.2.27 antibody, N-recognin-2 antibody, RING-type E3 ubiquitin transferase UBR2 antibody, Ubiquitin-protein ligase E3-alpha-2 antibody, Ubiquitin-protein ligase E3-alpha-II antibody

UniProt: Q8IWV8