EHD1 anticorps (AA 401-498)

N° du produit ABIN7151453

Cet anticorps Lapin Polyclonal détecte spécifiquement EHD1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour EHD1 anticorps (AA 401-498) (ABIN7151453)

Antigène: EHD1 (EH-Domain Containing 1 (EHD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EHD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EHD1 anticorps

Épitope: AA 401-498

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human EH domain-containing protein 1 protein (401-498AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EHD1

Antigène: EHD1 (EH-Domain Containing 1 (EHD1))

Autre désignation: EHD1

Sujet:

Background: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes (PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis (PubMed:25686250).

Aliases: CDABP0131 antibody, EH domain containing 1 antibody, EH domain-containing protein 1 antibody, EHD1 antibody, EHD1_HUMAN antibody, FLJ42622 antibody, FLJ44618 antibody, H PAST antibody, hPAST1 antibody, PAST antibody, PAST homolog 1 antibody, PAST1 antibody, Testilin antibody

UniProt: Q9H4M9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development