Elf4 anticorps (AA 1-200)
Aperçu rapide pour Elf4 anticorps (AA 1-200) (ABIN7152098)
Antigène
Voir toutes Elf4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-200
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Fonction
- ELF4 Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Elf4 (E74 like ETS transcription factor 4 (Elf4))
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Autre désignation
- ELF4
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Sujet
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Background: Transcriptional activator that binds to DNA sequences containing the consensus 5\\\'-WGGA-3\\\'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Aliases: E74-like factor 4 antibody, ELF4 antibody, ELF4_HUMAN antibody, ELFR antibody, ETS-related transcription factor Elf-4 antibody, ETS-related transcription factor Elf4 antibody, MEF antibody, Myeloid Elf-1-like factor antibody, Myeloid Elf1-like factor antibody
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UniProt
- Q99607
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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