EIF3S1 anticorps (AA 5-115)

N° du produit ABIN7152166

Cet anticorps anti-EIF3S1 Polyclonal Lapin (ABIN7152166) détecte spécifiquement EIF3S1 dans ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EIF3S1 anticorps (AA 5-115) (ABIN7152166)

Antigène: EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3S1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EIF3S1 anticorps

Épitope: AA 5-115

Fonction: EIF3J Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Eukaryotic translation initiation factor 3 subunit J protein (5-115AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EIF3S1

Antigène: EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))

Autre désignation: EIF3J

Sujet:

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.

Aliases: eIF 3 alpha antibody, eIF-3-alpha antibody, eIF3 alpha antibody, eIF3 p35 antibody, eIF3j antibody, EIF3J_HUMAN antibody, EIF3S 1 antibody, EIF3S1 antibody, Eukaryotic translation initiation factor 3 subunit 1 antibody, Eukaryotic translation initiation factor 3 subunit J antibody, Eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD) antibody, Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kD antibody

UniProt: O75822

Pathways: Ribonucleoprotein Complex Subunit Organization