Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 2-374) anticorps
Aperçu rapide pour Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 2-374) anticorps (ABIN7152172)
Antigène
Voir toutes Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 2-374
-
Fonction
- EIF3M Antibody
-
Réactivité croisée
- Rat
-
Purification
- Protein G purified
-
Pureté
- >95 %
-
Immunogène
- Recombinant Human Eukaryotic translation initiation factor 3 subunit M protein (2-374AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
-
Autre désignation
- EIF3M
-
Sujet
-
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
Aliases: B5 antibody, B5 receptor antibody, Dendritic cell protein antibody, eIF3m antibody, EIF3M_HUMAN antibody, Eukaryotic translation initiation factor 3 subunit M antibody, Fetal lung protein B5 antibody, FLJ29030 antibody, GA17 antibody, hfl B5 antibody, hFL-B5 antibody, PCI domain containing 1 (herpesvirus entry mediator) antibody, PCI domain-containing protein 1 antibody, PCID1 antibody, TANGO7 antibody
-
UniProt
- Q7L2H7
-
Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
-