F-Box Protein 3 anticorps (AA 276-376) (HRP)

N° du produit ABIN7152428

Cet anticorps Lapin Polyclonal détecte spécifiquement F-Box Protein 3 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour F-Box Protein 3 anticorps (AA 276-376) (HRP) (ABIN7152428)

Antigène: F-Box Protein 3 (FBXO3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F-Box Protein 3 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-F-Box Protein 3 anticorps (HRP)

Épitope: AA 276-376

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human F-box only protein 3 protein (276-376AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur F-Box Protein 3

Antigène: F-Box Protein 3 (FBXO3)

Autre désignation: FBXO3

Sujet:

Background: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Aliases: F Box G - Domain 3 antibody, F box only protein 3 antibody, F box protein 3 antibody, F box protein FBX3 antibody, F-box only protein 3 antibody, FBA antibody, FBX3 antibody, FBX3_HUMAN antibody, FBXO3 antibody

UniProt: Q9UK99