SUPT16H anticorps (AA 187-282) (FITC)

N° du produit ABIN7152515

Cet anticorps Lapin Polyclonal détecte spécifiquement SUPT16H dans . Il présente une réactivité envers Humain.

Aperçu rapide pour SUPT16H anticorps (AA 187-282) (FITC) (ABIN7152515)

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT16H est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-SUPT16H anticorps (FITC)

Épitope: AA 187-282

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human FACT complex subunit SPT16 protein (187-282AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SUPT16H

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Autre désignation: SUPT16H

Sujet:

Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of \'Ser-392\' of p53/TP53 via its association with CK2 (casein kinase II).

Aliases: CDC68 antibody, Chromatin specific transcription elongation factor 140 kDa subunit antibody, Chromatin-specific transcription elongation factor 140 kDa subunit antibody, Facilitates chromatin transcription complex subunit SPT16 antibody, FACT 140 kDa subunit antibody, FACT antibody, FACT complex subunit SPT16 antibody, FACTp140 antibody, FLJ10857 antibody, FLJ14010 antibody, hSPT16 antibody, SP16H_HUMAN antibody, Suppressor of Ty 16 homolog antibody, Supt16h antibody

UniProt: Q9Y5B9

Pathways: Chromatin Binding