FGG anticorps (AA 278-437)

N° du produit ABIN7152763

Cet anticorps anti-FGG est un anticorps Lapin Polyclonal détectant FGG dans WB, IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour FGG anticorps (AA 278-437) (ABIN7152763)

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-FGG anticorps

Épitope: AA 278-437

Fonction: FGG Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Fibrinogen gamma chain protein (278-437AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FGG

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Autre désignation: FGG

Sujet:

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Aliases: FGG antibody, FIBG_HUMAN antibody, Fibrinogen gamma chain antibody, Fibrinogen gamma polypeptide antibody, fibrinogen gamma-b chain antibody

UniProt: P02679