FOXN4 anticorps (AA 89-194) (FITC)
Aperçu rapide pour FOXN4 anticorps (AA 89-194) (FITC) (ABIN7153078)
Antigène
Voir toutes FOXN4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 89-194
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Fonction
- FOXN4 Antibody, FITC conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Forkhead box protein N4 protein (89-194AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FOXN4 (Forkhead Box N4 (FOXN4))
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Autre désignation
- FOXN4
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Sujet
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Background: Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5\'-ACGC-3\'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).
Aliases: FOXN4Forkhead box protein N4 antibody
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UniProt
- Q96NZ1
Antigène
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