FFAR1 anticorps (AA 143-178) (Biotin)

N° du produit ABIN7153160

Cet anticorps Lapin Polyclonal détecte spécifiquement FFAR1 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour FFAR1 anticorps (AA 143-178) (Biotin) (ABIN7153160)

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FFAR1 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-FFAR1 anticorps (Biotin)

Épitope: AA 143-178

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Free fatty acid receptor 1 protein (143-178AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FFAR1

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Autre désignation: FFAR1

Sujet:

Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

Aliases: FFA1R antibody, FFAR 1 antibody, Ffar1 antibody, FFAR1_HUMAN antibody, Free fatty acid receptor 1 antibody, G protein coupled receptor 40 antibody, G-protein coupled receptor 40 antibody, GPCR40 antibody, GPR 40 antibody, GPR40 antibody

UniProt: O14842

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis