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GPR161 anticorps (AA 1-28)

GPR161 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7153327
  • Antigène Voir toutes GPR161 Anticorps
    GPR161 (G Protein-Coupled Receptor 161 (GPR161))
    Épitope
    • 15
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-28
    Reactivité
    • 37
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 35
    • 2
    Lapin
    Clonalité
    • 35
    • 2
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GPR161 est non-conjugé
    Application
    • 30
    • 13
    • 13
    • 12
    • 11
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
    Isotype
    IgG
    Top Product
    Discover our top product GPR161 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    GPR161 (G Protein-Coupled Receptor 161 (GPR161))
    Autre désignation
    GPR161 (GPR161 Produits)
    Synonymes
    anticorps RE2, anticorps Gm208, anticorps Gm208Gpr, anticorps vl, anticorps RGD1563245, anticorps si:bz20i5.4, anticorps si:rp71-20i5.4, anticorps G protein-coupled receptor 161, anticorps GPR161, anticorps Gpr161, anticorps gpr161
    Sujet

    Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

    Aliases: GPR161 antibody, G-protein coupled receptor 161 antibody, G-protein coupled receptor RE2 antibody

    UniProt
    Q8N6U8
    Pathways
    cAMP Metabolic Process
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