GABARAPL2 anticorps (AA 1-117) (Biotin)
Aperçu rapide pour GABARAPL2 anticorps (AA 1-117) (Biotin) (ABIN7153523)
Antigène
Voir toutes GABARAPL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-117
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 protein (1-117AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
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Autre désignation
- GABARAPL2
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Sujet
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Background: Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Aliases: ATG8 antibody, ATG8C antibody, FLC3A antibody, GABA(A) receptor-associated protein-like 2 antibody, Gabarapl2 antibody, Gamma-aminobutyric acid receptor-associated protein-like 2 antibody, Ganglioside expression factor 2 antibody, GATE-16 antibody, GATE16 antibody, GBRL2_HUMAN antibody, GEF-2 antibody, GEF2 antibody, General protein transport factor p16 antibody, Golgi-associated ATPase enhancer of 16 kDa antibody, MAP1 light chain 3-related protein antibody
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UniProt
- P60520
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Pathways
- Autophagy
Antigène
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