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WDR24 anticorps (AA 1-298) (Biotin)

WDR24 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7153706
  • Antigène Tous les produits WDR24
    WDR24 (WD Repeat Domain 24 (WDR24))
    Épitope
    • 3
    • 1
    AA 1-298
    Reactivité
    • 7
    • 1
    Humain
    Hôte
    • 7
    Lapin
    Clonalité
    • 7
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    Cet anticorp WDR24 est conjugé à/à la Biotin
    Application
    • 4
    • 4
    • 3
    • 2
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human GATOR complex protein WDR24 protein (1-298AA)
    Isotype
    IgG
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    WDR24 (WD Repeat Domain 24 (WDR24))
    Autre désignation
    WDR24 (WDR24 Produits)
    Synonymes
    anticorps C16orf21, anticorps JFP7, anticorps BC037651, anticorps wu:fd05f12, anticorps zgc:55946, anticorps WD repeat domain 24, anticorps WD repeat domain 24 L homeolog, anticorps WDR24, anticorps Wdr24, anticorps wdr24, anticorps wdr24.L
    Sujet

    Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).

    Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody

    UniProt
    Q96S15
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