WDR59 anticorps (AA 619-862) (Biotin)
Aperçu rapide pour WDR59 anticorps (AA 619-862) (Biotin) (ABIN7153710)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 619-862
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WDR59 (WD Repeat Domain 59 (WDR59))
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Autre désignation
- WDR59
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Sujet
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Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
Aliases: WDR59 antibody, KIAA1923 antibody, FP977 antibody, GATOR complex protein WDR59 antibody, WD repeat-containing protein 59 antibody
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UniProt
- Q6PJI9
Antigène
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