SIP1 anticorps (AA 1-280)

N° du produit ABIN7153753

Détail du produit anti-SIP1 anticorps

Antigène: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Épitope: AA 1-280

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Gem-associated protein 2 protein (1-280AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SIP1

Antigène: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Autre désignation: GEMIN2 (GEMIN2 Produits)

Synonymes: anticorps SIP1, anticorps SIP1-delta, anticorps 1700012N19Rik, anticorps Sip1, anticorps sip1, anticorps sip1-delta, anticorps wu:fc52a05, anticorps zgc:110274, anticorps gem nuclear organelle associated protein 2, anticorps gem (nuclear organelle) associated protein 2, anticorps gem nuclear organelle associated protein 2 S homeolog, anticorps GEMIN2, anticorps Gemin2, anticorps gemin2.S, anticorps gemin2

Sujet:

Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Aliases: Component of gems 2 antibody, Gem (nuclear organelle) associated protein 2 antibody, Gem associated protein 2 antibody, GEMI2_HUMAN antibody, Gemin-2 antibody, gemin2 antibody, SIP 1 antibody, SIP-1 antibody, SIP1 antibody, SIP1 delta antibody, SIP1-delta antibody, SMN interacting protein 1 antibody, SMN interacting protein 1 delta antibody, SMN-interacting protein 1 antibody, Survival interacting protein 1 antibody, Survival of motor neuron protein interacting protein 1 antibody, Survival of motor neuron protein-interacting protein 1 antibody

UniProt: O14893

Pathways: Ribonucleoprotein Complex Subunit Organization, Tube Formation