GEMIN8 anticorps (AA 1-242)

N° du produit ABIN7153769

Cet anticorps Lapin Polyclonal détecte spécifiquement GEMIN8 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour GEMIN8 anticorps (AA 1-242) (ABIN7153769)

Antigène: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GEMIN8 anticorps

Épitope: AA 1-242

Fonction: GEMIN8 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Gem-associated protein 8 protein (1-242AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GEMIN8

Antigène: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Autre désignation: GEMIN8

Sujet:

Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Aliases: GEMIN8 antibody, FAM51A1Gem-associated protein 8 antibody, Gemin-8 antibody, Protein FAM51A1 antibody

UniProt: Q9NWZ8

Pathways: Ribonucleoprotein Complex Subunit Organization