Glutaredoxin 2 anticorps (AA 1-124)

N° du produit ABIN7154050

Détail du produit anti-Glutaredoxin 2 anticorps

Antigène: Glutaredoxin 2 (GRX2)

Épitope: AA 1-124

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Glutaredoxin-2, mitochondrial protein (1-124AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Glutaredoxin 2

Antigène: Glutaredoxin 2 (GRX2)

Autre désignation: GLRX2 (GRX2 Produits)

Synonymes: anticorps ECK1049, anticorps JW1051, anticorps CGI-133, anticorps GRX2, anticorps 1700010P22Rik, anticorps AI645710, anticorps Grx2, anticorps glutaredoxin 2 (Grx2), anticorps glutaredoxin Grx2, anticorps thioredoxin, anticorps glutaredoxin 2, anticorps glutaredoxin 2 (thioltransferase), anticorps grxB, anticorps grx2, anticorps AF_RS10790, anticorps GLRX2, anticorps Glrx2

Sujet:

Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

Aliases: bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2) antibody, bA101E13.1 antibody, CGI133 antibody, Glrx2 antibody, GLRX2_HUMAN antibody, Glutaredoxin-2 antibody, Glutaredoxin-2, mitochondrial antibody, GRX2 antibody, mitochondrial antibody

UniProt: Q9NS18

Pathways: Cell RedoxHomeostasis