GLRB anticorps (AA 355-472)

N° du produit ABIN7154190

L’anticorps anti-GLRB Polyclonal produit chez le Lapin a été validé pour ELISA et IF. Il convient pour la détection de GLRB dans des échantillons provenant de Humain. }

Aperçu rapide pour GLRB anticorps (AA 355-472) (ABIN7154190)

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLRB est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-GLRB anticorps

Épitope: AA 355-472

Fonction: GLRB Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Glycine receptor subunit beta protein (355-472AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GLRB

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Autre désignation: GLRB

Sujet:

Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

Aliases: GLRBGlycine receptor subunit beta antibody, Glycine receptor 58 kDa subunit antibody

UniProt: P48167