GPC1 anticorps (AA 342-530)

N° du produit ABIN7154264

Cet anticorps Lapin Polyclonal détecte spécifiquement GPC1 dans ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour GPC1 anticorps (AA 342-530) (ABIN7154264)

Antigène: GPC1 (Glypican 1 (GPC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPC1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GPC1 anticorps

Épitope: AA 342-530

Fonction: GPC1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Glypican-1 protein (342-530AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GPC1

Antigène: GPC1 (Glypican 1 (GPC1))

Autre désignation: GPC1

Sujet:

Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Aliases: FLJ38078 antibody, glypican antibody, Glypican proteoglycan 1 antibody, glypican1 antibody, GPC 1 antibody, Gpc1 antibody, GPC1_HUMAN antibody, Secreted glypican-1 antibody

UniProt: P35052

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation