GPC1 anticorps (AA 342-530)

N° du produit ABIN7154264

Détail du produit anti-GPC1 anticorps

Antigène: GPC1 (Glypican 1 (GPC1))

Épitope: AA 342-530

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPC1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Glypican-1 protein (342-530AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GPC1

Antigène: GPC1 (Glypican 1 (GPC1))

Autre désignation: GPC1 (GPC1 Produits)

Synonymes: anticorps gpc1, anticorps zgc:63947, anticorps GPC1, anticorps Glypican-1, anticorps glypican, anticorps AI462976, anticorps HSPG M12, anticorps HSPGM12, anticorps glypican 1b, anticorps glypican 1, anticorps gpc1b, anticorps GPC1, anticorps gpc1, anticorps Gpc1

Sujet:

Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Aliases: FLJ38078 antibody, glypican antibody, Glypican proteoglycan 1 antibody, glypican1 antibody, GPC 1 antibody, Gpc1 antibody, GPC1_HUMAN antibody, Secreted glypican-1 antibody

UniProt: P35052

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation