GRB14 anticorps (AA 294-397)

N° du produit ABIN7154498

Cet anticorps Lapin Polyclonal détecte spécifiquement GRB14 dans ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour GRB14 anticorps (AA 294-397) (ABIN7154498)

Antigène: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRB14 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GRB14 anticorps

Épitope: AA 294-397

Fonction: GRB14 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Growth factor receptor-bound protein 14 protein (294-397AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRB14

Antigène: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Autre désignation: GRB14

Sujet:

Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Aliases: GRB14Growth factor receptor-bound protein 14 antibody, GRB14 adapter protein antibody

UniProt: Q14449