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PDE8A anticorps (AA 596-829)

PDE8A Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7155164
  • Antigène Voir toutes PDE8A Anticorps
    PDE8A (phosphodiesterase 8A (PDE8A))
    Épitope
    • 12
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 596-829
    Reactivité
    • 47
    • 11
    • 11
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 43
    • 4
    Lapin
    Clonalité
    • 44
    • 3
    Polyclonal
    Conjugué
    • 25
    • 6
    • 6
    • 4
    • 3
    • 3
    Cet anticorp PDE8A est non-conjugé
    Application
    • 29
    • 28
    • 27
    • 8
    • 7
    • 7
    • 6
    • 6
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3\',5\'-cyclic phosphodiesterase 8A protein (596-829AA)
    Isotype
    IgG
    Top Product
    Discover our top product PDE8A Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    PDE8A (phosphodiesterase 8A (PDE8A))
    Autre désignation
    PDE8A (PDE8A Produits)
    Synonymes
    anticorps PDE8A, anticorps Pde8a, anticorps HsT19550, anticorps AI551852, anticorps Pde8, anticorps RNPDE8A, anticorps phosphodiesterase 8A, anticorps PDE8A, anticorps Pde8a, anticorps pde8a
    Sujet

    Background: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 \'Ser-259\' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299).

    Aliases: 5''-cyclic phosphodiesterase 8A antibody, cAMP specific cyclic nucleotide phosphodiesterase 8A antibody, FLJ16150 antibody, High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A antibody, High affinity cAMP-specific and IBMX-insensitive 3'' antibody, HsT19550 antibody, PDE 8A antibody, PDE8A antibody, PDE8A_HUMAN antibody, Phosphodiesterase 8A antibody, Phosphodiesterase8A antibody, Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody

    UniProt
    O60658
    Pathways
    cAMP Metabolic Process
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