HMGB3 anticorps (AA 1-103)

N° du produit ABIN7155213

Détail du produit anti-HMGB3 anticorps

Antigène: HMGB3 (High Mobility Group Box 3 (HMGB3))

Épitope: AA 1-103

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human High mobility group protein B3 protein (1-103AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HMGB3

Antigène: HMGB3 (High Mobility Group Box 3 (HMGB3))

Autre désignation: HMGB3 (HMGB3 Produits)

Synonymes: anticorps HMG-2a, anticorps HMG-4, anticorps HMG2A, anticorps HMG4, anticorps Hmg2a, anticorps Hmg4, anticorps RGD1564407, anticorps hmgb3, anticorps MGC54022, anticorps Xhmgb3, anticorps MGC88931, anticorps fa19b06, anticorps fj43d02, anticorps wu:fa19b06, anticorps wu:fj43d02, anticorps zgc:112073, anticorps HMGB3, anticorps NFD03, anticorps NFD3, anticorps NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR, anticorps high mobility group B3, anticorps HMG-1, anticorps HMG2a, anticorps HMGB1, anticorps high mobility group box 3, anticorps high mobility group box 3b, anticorps high mobility group box 3 S homeolog, anticorps high mobility group protein, anticorps high mobility group B3, anticorps High mobility group protein B3, anticorps HMGB3, anticorps Hmgb3, anticorps hmgb3, anticorps hmgb3b, anticorps hmgb3.S

Sujet:

Background: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).

Aliases: chromosomal protein, Nonhistone, HMG4 antibody, High mobility group (nonhistone chromosomal) protein 4 antibody, High mobility group box 3 antibody, High mobility group protein 2a antibody, High mobility group protein 4 antibody, High mobility group protein B3 antibody, High mobility group protein HMG4 antibody, HMG 4 antibody, HMG-2a antibody, HMG-4 antibody, HMG2A antibody, HMGB 3 antibody, Hmgb3 antibody, HMGB3_HUMAN antibody, MGC90319 antibody, Non histone chromosomal protein antibody, Nonhistone chromosomal protein HMG4 antibody

UniProt: O15347