H2AFB1 anticorps (AA 1-115)
Aperçu rapide pour H2AFB1 anticorps (AA 1-115) (ABIN7155373)
Antigène
Voir toutes H2AFB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-115
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Fonction
- H2AFB1 Antibody
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
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Autre désignation
- H2AFB1
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Sujet
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Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.
Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody
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UniProt
- P0C5Y9
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Pathways
- Telomere Maintenance
Antigène
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