EZH1 anticorps (AA 160-280)

N° du produit ABIN7155474

L’anticorps Lapin Polyclonal anti-EZH1 a été validé pour ELISA et IHC. Il convient pour détecter EZH1 dans des échantillons de Humain.

Aperçu rapide pour EZH1 anticorps (AA 160-280) (ABIN7155474)

Antigène: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EZH1 anticorps

Épitope: AA 160-280

Fonction: EZH1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EZH1

Antigène: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Autre désignation: EZH1

Sujet:

Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Aliases: Enhancer of zeste homolog 1 (Drosophila) antibody, Enhancer of zeste homolog 1 antibody, ENX-2 antibody, ENX2 antibody, Ezh1 antibody, EZH1_HUMAN antibody, Histone-lysine N-methyltransferase EZH1 antibody

UniProt: Q92800