MEOX1 anticorps (AA 1-254)

N° du produit ABIN7155798

L’anticorps Lapin Polyclonal anti-MEOX1 a été validé pour ELISA et IHC. Il convient pour détecter MEOX1 dans des échantillons de Humain.

Aperçu rapide pour MEOX1 anticorps (AA 1-254) (ABIN7155798)

Antigène: MEOX1 (Mesenchyme Homeobox 1 (MEOX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEOX1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MEOX1 anticorps

Épitope: AA 1-254

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Homeobox protein MOX-1 protein (1-254AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MEOX1

Antigène: MEOX1 (Mesenchyme Homeobox 1 (MEOX1))

Autre désignation: MEOX1

Sujet:

Background: Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.

Aliases: Homeobox protein MOX-1 antibody, MEOX1 antibody, MEOX1_HUMAN antibody, Mesenchyme homeo box 1 antibody, Mesenchyme homeobox 1 antibody, MOX 1 antibody, MOX1 antibody

UniProt: P50221

Pathways: Chromatin Binding