Nanog anticorps (AA 1-305) (HRP)
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- Antigène Voir toutes Nanog (NANOG) Anticorps
- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Épitope
- AA 1-305
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Nanog est conjugé à/à la HRP
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Homeobox protein NANOG protein (1-305AA)
- Isotype
- IgG
- Top Product
- Discover our top product NANOG Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Autre désignation
- NANOG (NANOG Produits)
- Synonymes
- anticorps 2410002E02Rik, anticorps ENK, anticorps ecat4, anticorps NANOG, anticorps hacp, anticorps wu:fd19e04, anticorps wu:fd20a07, anticorps zgc:193933, anticorps Nanog homeobox, anticorps nanog homeobox, anticorps Nanog, anticorps NANOG, anticorps nanog
- Sujet
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Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5\'-TAAT[GT][GT]-3\' or 5\'-[CG][GA][CG]C[GC]ATTAN[GC]-3\'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
Aliases: Embryonic stem cell specific homeobox protein (Nanog) antibody, ENK antibody, FLJ12581 antibody, hNanog antibody, Homeobox protein NANOG antibody, Homeobox transcription factor Nanog antibody, homeobox transcription factor Nanog-delta 48 antibody, NANOG antibody, Nanog homeobox antibody, NANOG_HUMAN antibody
- UniProt
- Q9H9S0
- Pathways
- Stem Cell Maintenance
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