HORMAD1 anticorps (AA 201-394)

N° du produit ABIN7155897

L’anticorps Lapin Polyclonal anti-HORMAD1 a été validé pour ELISA. Il convient pour détecter HORMAD1 dans des échantillons de Humain.

Aperçu rapide pour HORMAD1 anticorps (AA 201-394) (ABIN7155897)

Antigène: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HORMAD1 est non-conjugé

Application: ELISA

Détail du produit anti-HORMAD1 anticorps

Épitope: AA 201-394

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human HORMA domain-containing protein 1 protein (201-394AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HORMAD1

Antigène: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Autre désignation: HORMAD1

Sujet:

Background: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

Aliases: HORMAD1 antibody, NOHMA antibody, HORMA domain-containing protein 1 antibody, Cancer/testis antigen 46 antibody, CT46 antibody, Newborn ovary HORMA protein antibody

UniProt: Q86X24

Pathways: M Phase