KPNA6 anticorps (AA 277-536)

N° du produit ABIN7156132

Cet anticorps anti-KPNA6 est un anticorps Lapin Polyclonal détectant KPNA6 dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour KPNA6 anticorps (AA 277-536) (ABIN7156132)

Antigène: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-KPNA6 anticorps

Épitope: AA 277-536

Fonction: KPNA6 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Importin subunit alpha-7 protein (277-536AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KPNA6

Antigène: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Autre désignation: KPNA6

Sujet:

Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

Aliases: FLJ11249 antibody, IMA7_HUMAN antibody, Importin alpha 7 subunit antibody, Importin alpha S2 antibody, Importin subunit alpha 7 antibody, Importin subunit alpha-7 antibody, IPOA 7 antibody, IPOA7 antibody, Karyopherin alpha 6 antibody, Karyopherin alpha 6 (importin alpha 7) antibody, Karyopherin subunit alpha 6 antibody, Karyopherin subunit alpha-6 antibody, KPNA 6 antibody, KPNA 7 antibody, Kpna6 antibody, KPNA7 antibody, MGC17918 antibody, OTTHUMP00000004532 antibody

UniProt: O60684

Pathways: Protein targeting to Nucleus