Importin 11 anticorps (AA 1-270) (FITC)

N° du produit ABIN7156140

L’anticorps Lapin Polyclonal anti-Importin 11 a été validé pour . Il convient pour détecter Importin 11 dans des échantillons de Humain.

Aperçu rapide pour Importin 11 anticorps (AA 1-270) (FITC) (ABIN7156140)

Antigène: Importin 11 (IPO11)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 11 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-Importin 11 anticorps (FITC)

Épitope: AA 1-270

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Importin-11 protein (1-270AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Importin 11

Antigène: Importin 11 (IPO11)

Autre désignation: IPO11

Sujet:

Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).

Aliases: Imp11 antibody, Importin 11 antibody, Importin-11 antibody, IPO11 antibody, IPO11_HUMAN antibody, Ran binding protein 11 antibody, Ran-binding protein 11 antibody, RanBP11 antibody, SLRN antibody, Synleurin antibody

UniProt: Q9UI26

Pathways: Protein targeting to Nucleus