FKBP6 anticorps (AA 101-327) (HRP)
Aperçu rapide pour FKBP6 anticorps (AA 101-327) (HRP) (ABIN7156158)
Antigène
Voir toutes FKBP6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-327
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Fonction
- FKBP6 Antibody, HRP conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Inactive peptidyl-prolyl cis-trans isomerase FKBP6 protein (101-327AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))
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Autre désignation
- FKBP6
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Sujet
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Background: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.
Aliases: 36 kDa FK506 binding protein antibody, 36 kDa FK506-binding protein antibody, 36 kDa FKBP antibody, EC 5.2.1.8 antibody, FK506 binding protein 6 antibody, FK506-binding protein 6 antibody, FKBP 36 antibody, FKBP-36 antibody, FKBP-6 antibody, FKBP36 antibody, fkbp6 antibody, FKBP6_HUMAN antibody, Immunophilin FKBP36 antibody, Peptidyl prolyl cis trans isomerase antibody, Peptidyl-prolyl cis-trans isomerase FKBP6 antibody, PPIase antibody, PPIase FKBP6 antibody, Rotamase antibody
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UniProt
- O75344
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Pathways
- M Phase
Antigène
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