ING3 anticorps (AA 51-223)
Aperçu rapide pour ING3 anticorps (AA 51-223) (ABIN7156249)
Antigène
Voir toutes ING3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 51-223
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Fonction
- ING3 Antibody
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Réactivité croisée
- Souris
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Inhibitor of growth protein 3 protein (51-223AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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Autre désignation
- ING3
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Sujet
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Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Aliases: ING3 antibody, HSPC301 antibody, Inhibitor of growth protein 3 antibody, p47ING3 antibody
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UniProt
- Q9NXR8
Antigène
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