Plexin B2 anticorps (AA 1458-1673) (FITC)
Aperçu rapide pour Plexin B2 anticorps (AA 1458-1673) (FITC) (ABIN7156270)
Antigène
Voir toutes Plexin B2 (PLXNB2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1458-1673
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Réactivité croisée
- Humain
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Purification
- >95%, Antigen Affinity purified & Affinity purified
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Immunogène
- Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Plexin B2 (PLXNB2)
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Autre désignation
- PLXNB2
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Sujet
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Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \'Tyr-1248\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).
Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody
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UniProt
- O15031
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Pathways
- Tube Formation
Antigène
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