ITPK1 anticorps (AA 185-414)

N° du produit ABIN7156320

L’anticorps Lapin Polyclonal anti-ITPK1 a été validé pour WB, ELISA et IHC. Il convient pour détecter ITPK1 dans des échantillons de Humain.

Aperçu rapide pour ITPK1 anticorps (AA 185-414) (ABIN7156320)

Antigène: ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITPK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ITPK1 anticorps

Épitope: AA 185-414

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Inositol-tetrakisphosphate 1-kinase protein (185-414AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ITPK1

Antigène: ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))

Autre désignation: ITPK1

Sujet:

Background: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

Aliases: 3 antibody, 4)P(3) 5/6-kinase antibody, 4-trisphosphate 5/6-kinase antibody, Inositol 1 3 4 triphosphate 5/6 kinase antibody, Inositol 1 3 4 trisphosphate 5/6 kinase antibody, Inositol 1 antibody, Inositol tetrakisphosphate 1 kinase antibody, Inositol triphosphate 5/6 kinase antibody, Inositol-tetrakisphosphate 1-kinase antibody, Inositol-triphosphate 5/6-kinase antibody, Ins(1 3 4)P(3) 5/6 kinase antibody, Ins(1 antibody, ITPK 1 antibody, itpk1 antibody, ITPK1_HUMAN antibody, ITRPK 1 antibody, ITRPK1 antibody

UniProt: Q13572