ITGA5 anticorps (AA 220-472)

N° du produit ABIN7156442

Cet anticorps Lapin Polyclonal détecte spécifiquement ITGA5 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour ITGA5 anticorps (AA 220-472) (ABIN7156442)

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ITGA5 anticorps

Épitope: AA 220-472

Fonction: ITGA5 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Integrin alpha-5 protein (220-472AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ITGA5

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Autre désignation: ITGA5

Sujet:

Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).

Aliases: CD49 antigen-like family member E antibody, CD49e antibody, Fibronectin receptor subunit alpha antibody, Fibronectin receptor, alpha subunit antibody, FNRA antibody, Integrin alpha 5 (fibronectin receptor alpha) antibody, Integrin alpha-5 antibody, Integrin alpha-5 light chain antibody, Integrin alpha-F antibody, Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody, ITA5_HUMAN antibody, Itga5 antibody, Very late activation protein 5, alpha subunit antibody, VLA-5 antibody, VLA5 antibody, VLA5A antibody

UniProt: P08648

Pathways: Integrin Complex