IL29 anticorps (AA 20-200)
Aperçu rapide pour IL29 anticorps (AA 20-200) (ABIN7156607)
Antigène
Voir toutes IL29 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 20-200
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Fonction
- IFNL1 Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Interferon lambda-1 protein (20-200AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IL29 (Interleukin 29 (IL29))
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Autre désignation
- IFNL1
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Sujet
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Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Aliases: IFNL1 antibody, IL29 antibody, ZCYTO21Interferon lambda-1 antibody, IFN-lambda-1 antibody, Cytokine Zcyto21 antibody, Interleukin-29 antibody, IL-29 antibody
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UniProt
- Q8IU54
Antigène
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