Inversin anticorps (AA 1-101)

N° du produit ABIN7157008

Détail du produit anti-Inversin anticorps

Antigène: Inversin (INVS)

Épitope: AA 1-101

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Inversin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Inversin protein (1-101AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Inversin

Antigène: Inversin (INVS)

Autre désignation: INVS (INVS Produits)

Synonymes: anticorps invs-a, anticorps INVS, anticorps MGC140477, anticorps inv, anticorps NPH2, anticorps NPHP2, anticorps INV, anticorps Nphp2, anticorps RGD1563359, anticorps wu:fe47e11, anticorps inversin S homeolog, anticorps inversin, anticorps Inversin, anticorps invs.S, anticorps INVS, anticorps Bm1_38710, anticorps PTRG_09181, anticorps EAMY_RS33690, anticorps LOAG_11716, anticorps invs, anticorps Invs

Sujet:

Background: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).

Aliases: INVS antibody, INV antibody, NPHP2 antibody, Inversin antibody, Inversion of embryo turning homolog antibody, Nephrocystin-2 antibody

UniProt: Q9Y283